Yu Liang

Director, Translational Sciences, Oncology

Yu Liang is a highly qualified professional, that works in Ipsen as a Director, Translational Sciences, Oncology from 2019. Yu Liang has earned professional experience in more than 17 positions at different companies. Yu Liang went to the New York University School of Medicine and got education from 1993 to 1999. San Francisco, California is the city, where this professional was lastly known to be living. Yu's phone number and email are accessed through Connexy on demand.
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Contact Information

Last Update
Jul 15, 2022
Email
li**@hotmail.com, su**@yahoo.com
Location
San Francisco, CA
Company
Ipsen

Workplace

Director, Translational Sciences, Oncology

Work History

Director, Translational Sciences, Oncology

Directs biomarker programs to support oncology development programs. Directs research to support rational drug combinations and new indications. Leads translational research team of pharm...
from Oct 2019

Director of Clinical Biomarkers

343 Oyster Point Blvd SUITE 200, South San Francisco, CA 94080
Building biomarker programs into clinical development of drugs that simultaneously target metabolism of both tumors and immune system including two leading first-in-class inhibitors of gluta...
May 2016 — Oct 2019

Clinical Biomarker Scientific Manager

1 Waukegan Rd, North Chicago, IL 60064
May 2014 — May 2016

Staff Scientist, Division of Molecular Medicine, Molecular Diagnostics

Foster City, CA
Jul 2011 — Feb 2013

Staff Scientist, Genomic Assays-R&D

Foster City, CA
Jul 2005 — Jul 2011

Staff Scientist

81 Wyman St, Waltham, MA 02451
2005 — 2011

Assistant Researcher, Brain Tumor Research Center, Department of Neurological Surgery

San Francisco, CA
Sep 2001 — Jun 2005

Assistant Researcher

505 Parnassus Ave, San Francisco, CA 94143
Pioneered using high throughput gene expression profiling and pre-clinical models to identify and validate clinically actionable biomarkers in brain tumor patients. Identified gene express...
2001 — 2005

Scientific Manager, Translational Medicine & Clinical Biomarker Program

2000 — 2014

Postdoctoral Fellow, Preuss Laboratory for Molecular Neuro

San Francisco, CA
1999 — 2001

Postdoctoral Fellow

505 Parnassus Ave, San Francisco, CA 94143
Collaborated with Stanford (Pat Brown’s Lab) and set up a microarray gene expression profiling system at UCSF Neurosurgery department to analyze clinical specimens procured by the BTRC Tumor...
1999 — 2001

Pre-Doctoral Research Fellow

550 1St Ave, New York, NY 10016
Biochemically purified and molecularly cloned a novel ligand of glypican, Slit, in mammalian brain, and characterized its expression patterns in mammalian central nervous system. - Identifie...
1993 — 1999

Research Associate

Mechanisms of desensitization of adenosine receptor. - Expression and subcellular localization of small GTP-binding proteins in pheochromocytoma cells.
1992 — 1993

Second Lieutenant, Combat and Operations Officer, Supervisory Officer

1990 — 1992

Reserve Officer Trainee

Training in basic and advanced military skills, weaponry, battle strategy, infantry specialty, and leadership development as part of the Reserve Officers Training Corps (ROTC).
1990 — 1990

Undergraduate Research Student

Subcloned T cell receptor gene from a T cell cDNA library through library screening. - Immunized mice with human T cells and generated hybridoma and screened them against the same T cells by...
1989 — 1990

Summer Student

Basic culture of Ganoderma lucidum (靈芝) and biochemical characterization of extracts from its fruit body.
1988 — 1988

Education

Ph.D. in Department of Pharmacology

New York, NY

B.Sc. in Department of Plant Pathology and Entomology

Occupations

Executive
Director
Doctor
Oncologist
Operations Manager
Medical Practice Professional
Medical Practitioner

Skills

Molecular Biology
Qpcr
Microarray
Biotechnology
Lifesciences
Real Time Pcr
Biomarker Discovery
Immunohistochemistry
Cancer Genomics
Pcr
Elisa
In Vitro
Gene Expression Profiling
Translational Research
Tissue Culture
Cancer Research
Molecular Diagnostics
Life Sciences
Data Mining
Bioinformatics
Confocal Microscopy
Brain Tumors
Immunocytochemistry
Business Integration
Flow Cytometry
Histopathology
Strategic Planning
In Situ Hybridization
Assay Development
Clinical Specimens Procurement
Meta Analysis
Cell Adhesion
Cell Migration
Tissue Processing
Marketing Research
Protein Purification
Dna Sequencing
Primary Cell Isolation
Biomarker Development
Product Development
Digital Image Processing
Transgenic Mice
Rodent Surgery
Hybridoma
Affinity Chromatography
Translational Medicine
PCR
real-time PCR
digital PCR for gene expression
genotyping
copy number
methylation
and allele-specific assays
microarray
sequencing
yeast two-hybrid system
library screening
sub-cloning
nucleic acid extraction from fresh and archived specimens
in vitro transcription and translation
real-time PCR instruments including low- and mid-density microfluidic platforms
robotics for high-throughput liquid handling. Meta-analysis of complex data from high-throughput genomic screening
comparative functional genomics and data mining for molecular profiling
statistic analyses of clinical data. Isolation and explant culture of primary tissues and their induced differentiation
migration
and adhesion
flow cytometry and FACS
immunohistochemistry
in situ hybridization
fluorescence and confocal laser microscopy
digital image analysis
procurement of clinical specimens and histological processing and sectioning. Animal breeding
genotyping of genetic modifications
immunization
general surgical procedure
transcardial perfusion and anatomical dissection
flank and intracranial xenograft
osmotic micropump implantation. IQOQPQ protocol writing and execution
compliance with QSR
ISO
and GLP. Cytokine assays
hybridoma and monoclonal antibody production
enzyme-linked and radio-immunoassays
receptor-ligand binding and enzyme activity assays
neurotransmitter secretion assays. Fractionation and concentration of recombinant and endogenous proteins
affinity chromatography
ion exchange
gel filtration
electrophoresis
Western. Bacterial
yeast
and fungal culture
antagonistic microbe screening
virus inoculation and viral particle purification.
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