Tripti Gaur is a highly qualified professional, who works in Mustang Bio main office of which is in 625. on the position of Director, Preclinical and Translational Sciences from 2020. Tripti has earned professional experience in more than 16 positions at different companies. Tripti Gaur went to the University of Delhi and received education from 2002. Worcester, Massachusetts is the city, where this professional was lastly known to live. Their phone number and email are easily accessed through Connexy by request.
Name variants:
Tripti Gaur
Contact Information
Last Update
Jul 5, 2022
Email
tr**@gmail.com, tr**@umassmed.edu
Location
Worcester, MA
Company
Mustang Bio
Workplace
Director, Preclinical and Translational Sciences
Work History
Associate Director and Biomarker Lead, Translational Pharmacology
610 Main St north, Cambridge, MA 02139
Sep 2019 — Sep 2020
Associate Director, Quantitative Translational Sciences
Bioanalytical and biomarker strategy set up for for various modalities including recombinant proteins, and AAV gene therapy, according to regulatory guidelines in support of preclinical and...
Jan 2019 — Sep 2019
Senior Scientist
Bioanalytical and biomarker strategy set up for for various modalities including recombinant proteins, and AAV gene therapy, according to regulatory guidelines in support of preclinical and...
Feb 2016 — Jul 2018
Senior Scientist, Pharmacology Amd Preclinical Development
55 Network Dr, Burlington, MA 01803
Conducted highthroughput biomarker discovery research for contact system disorders via external vendors/partners as well as internal studies, involving metabolomics, proteomics and microRNA...
Nov 2015 — Jan 2016
Research Scientist Ii - Senior Research Scientist
1320 Soldiers Field Rd, Boston, MA 02163
Team lead for Multiplex assay development, GLP/GCLP validation and samples testing for gene expression and biomarkers using qRT-PCR, Luminex-based cytokine and QuantiGene assays supporting ...
2014 — Oct 2015
Senior Scientist, Research and Development and Preclinical
First-hired bench scientist in R&D team, established fully functional cell culture facilities and molecular biology labs
Early Discovery Research for BMP signaling related new drug targets...
May 2012 — Jun 2014
Research Assistant Professor
55 Lake Ave north, Worcester, MA 01655
Understanding the in vivo role of microRNAs and their processing by Dicer during skeletal development
Use of antibody therapy and small molecule inhibitors for the improvement of injury re...
2010 — 2012
Instructor
55 Lake Ave north, Worcester, MA 01655
Mouse models of Wnt signaling for improvement of fracture healing
Signalling pathways for control of Breast cancer metastasis to bone
Epigenetic control of tumorigenic potential by bone-r...
2006 — 2009
Postdoctoral Fellow
55 Lake Ave north, Worcester, MA 01655
Role of Wnt antagonist sFRP1 in regulation of bone and cartilage formation and maintenance in mouse (in collaboration with Wyeth Research, now acquired by Pfizer)
2002 — 2006
Education
1997 — 2002
1990 — 1993
Occupations
Executive
Director
Deputy Director
Operations Manager
Deputy Manager
Chief Executive
Skills
Molecular Biology
Cell Biology
In Vitro
In Vivo
Cell Culture
Assay Development
Cancer Research
Animal Models
Elisa
Rt Pcr
Transfection
Western Blotting
Pcr
Molecular Cloning
Cell Signaling
Tissue Culture
Qpcr
Drug Discovery
Genetics
Microscopy
Immunoprecipitation
Immunohistochemistry
Fluorescence Microscopy
Immunofluorescence
Immunoassays
Rna Isolation
Sds Page
Drug Testing
Wound Healing
Recombinant Dna Technology
Fplc
Primary Cell Culture and Differentiation
Chromatin Immunoprecipitation
Cell Based Elisa
Small Molecules
Biomarker Analysis
Developmental Biology
Histology
Cell Cycle
Regenerative Medicine
Translational Research
Microrna
Project Management
Small Animal Surgery
Gene Silencing
Luminex
Microct
Sirna
Hplc/Uplc
Glp
Drug Discovery and Pharmacology: PK/PD assay development and validation under GLP conditions
biomarker analyses for safety/toxicology studies
cell-based and immuno-assays. as well as hit-to-lead testing/optimization of non-biologics small molecules for drug development
mouse models of tissue injury
and autoimmune diseases including rheumatoid arthritis and Lupus
radiography
microCT
IVIS imaging
small animal surgical techniques for xenografts and in vivo drug testing by localized and systemic injection
biomarker analysis. Molecular Biology: DNA isolation and manipulation (PCR
cloning
library screening
sequencing
Southern blotting)
recombinant vector construction and protein expression
RNA isolation from cells and tissues
phenotypic analysis by RT-PCR
qRT-PCR
Northern blot and microarray
microRNA isolation and expression studies
secreted microRNA analysis from plasma and serum samples
siRNA/shRNA-mediated gene silencing
immunoprecipitation
western blotting
Chromatin immunoprecipitation
FPLC
HPLC/UPLC. Cell Biology & Immunology: Mammalian cell culture
primary mesenchymal stem cell isolation and differentiation of 2D and 3D cell culture
cell differentiation into muscle
fat and bone lineage
transient and stable transfection
stable cell line generation
in vitro predictive immune response assays
enzymatic and reporter gene assays
cell-based ELISA
multiplexed analysis of cell surface and intracellular molecules by flow cytometry/FACS
biomarker analysis and gene expression profiling using Luminex
automated liquid handling (Apricot)
stable cell line generation using viral transduction
immunofluorescent staining and microscopy
histological processing for paraffin
frozen and plastic sectioning
various histochemical staining
immunohistochemistry
immunocytochemistry
signaling pathway analysis. Oncology: proliferation
invasion
migration studies
3D tumorosphere culture for cancer stem cell niche propagation
EMT marker analysis
in vivo xenograft implantation in rodents (subcutaneous
mammary fat pad injection and intra-bone inoculation. Project Management: Managed in vitro research activities for R&D
managed immunoassay development and sample testing for preclinical research via contract research organization
managed external collaborations for new product development. Computer Skills: xPONENT
Bioplex Manager
Softmax Pro
CellQuest Pro
high throughput data analyses from microarray studies
R-studio
pathway analysis using online tools
Microsoft Office Suite: Word
Excel
Access and PowerPoint
Adobe Creative Suite: Photoshop
Illustrator
Acrobat